منابع مشابه
Antiphospholipid Syndrome in Pregnancy
The antiphospholipid syndrome (APS) is a multisystemic disease, characterized by venous or arterial thromboses, or certain obstetric complications, and the presence of antiphospholipid antibodies (APAs)(1-4). APAs are a heterogeneous group of autoantibodies that bind to negatively charged phospholipids, phospholipid-binding protein, or a combination of the two. Lupus anticoagulant (LA), anticar...
متن کاملAntiphospholipid Antibodies and Antiphospholipid Syndrome during Pregnancy: Diagnostic Concepts
Antiphospholipid syndrome (APS) comprises of a wide spectrum of clinical and obstetric manifestations linked to the presence of antiphospholipid antibodies (aPL). APS was described in the context of lupus, and later as an isolated syndrome or primary APS. The presence of aPL, especially the lupus anticoagulant test, is associated with adverse pregnancy outcomes, such as fetal death, recurrent e...
متن کاملPredictors of pregnancy outcome in antiphospholipid syndrome: a review.
In pregnant women, antiphospholipid syndrome (APS) is associated with an increased risk of preeclampsia, fetal intrauterine growth restriction, and other complications related to uteroplacental insufficiency. In the last two decades, several studies were performed to identify the predictive role of some parameters in relation to obstetric outcome in APS patients. Among these, the uterine veloci...
متن کاملDiagnosis and management of antiphospholipid syndrome in pregnancy
Key content: • The diagnosis of antiphospholipid syndrome (APS) requires both characteristic clinical features and persistently abnormal laboratory tests. • Antiphospholipid syndrome can cause serious morbidity in mother and fetus. • Good management in an expert setting can result in a live birth rate of 80%. • Prepregnancy assessment and counselling play an important part in optimising the cha...
متن کاملObesity and Antiphospholipid Syndrome: A Particular Challenge in Pregnancy
Obesity is associated with a broad spectrum of chronic diseases, as well as cardiovascular diseases, such as diabetes, dyslipidemia, insulin resistance and hyperglycemia. Obesity during pregnancy is of major concern due to the well-known risk factors for both the mother and the child. Complications in pregnancy include recurrent miscarriages, gestational diabetes, hypertensive disorders, thromb...
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ژورنال
عنوان ژورنال: Expert Review of Obstetrics & Gynecology
سال: 2010
ISSN: 1747-4108,1747-4116
DOI: 10.1586/eog.10.57